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This includes sales of all electronic smoking devices: e-cigarettes, vapes, pod devices such as JUUL, e-liquids, and component parts and accessories.

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A pooled analysis of three cross-sectional studies ( n = 544) reported that ever-smokers had a threefold higher risk of advanced liver fibrosis compared to non-smokers (pooled OR: 3.00

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In just over 640 pages, the 1988 US Surgeon Generals report set out the evidence that nicotine was an addictive drug.[24] Eventually, this led to an investigation by the Food and Drug Administration in the mid-1990s seeking to deem, and then control, any new devices as drug delivery systems and so subject them to medical regulation