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The statutory definition of drugs under the FDA law refers to articles (other than food) intended to affect the structure or any function of the body. Kesslers team would spend the next several years documenting both that nicotine affects the structure or function of the body and that the tobacco industry intends it to have that effect

Some of these health problems only commonly occur in cases of heavy smoking, and while certain symptoms might be worth a doctors visit, others are entirely benign

Chemicals and flavours are added to products that have nicotine to reduce these effects

Some US-based tobacco companies and growers groups took action in 2014 to ban employing children under 16 to work in tobacco farming, but excluded older teens from their policies

However, the increased vapor production associated with low-voltage vaping may encourage more frequent inhalation, potentially leading to a higher cumulative nicotine intake