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Cut up for smoking, they were deficient in flavour, but were considered satisfactory as a first experiment

The substantial association between early initiation and severe dependence contributes to a significant public health burden

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Bonnie Halpern-Felsher, a professor of pediatrics at Stanford University, raised questions about the integrity of the French study by pointing out that Changeux has ties to the tobacco industry, having previously accepted $220,000 from the tobacco industry-funded Council for Tobacco Research in the 1990s, and collaborated with RJ Reynolds and Philip Morris.