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Symptoms will depend on: the type of substance you have been taking how long you have used it for your age your physical health your mental and emotional state the withdrawal process used Withdrawal symptoms can include: cravings problems with sleep irritability or agitation feeling restless trouble concentrating mood changes feeling depressed or anxious Physical symptoms can include: headaches aches and pains nausea, vomiting or diarrhoea sweating tremors or shaking Severe withdrawal symptoms can include: Withdrawal symptoms can last for a few days or weeks