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A reliance on animal experiments may be misleading, given the substantial changes, not only in UA metabolism but also in its transport, associated with primate evolution 62

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In 2014, the Centers for Disease Control and Prevention reported that only 37% of Maryland youth were asked to provide photo identification when purchasing cigarettes, and nearly 70% of youth smokers reported being able to illegally purchase cigarettes themselves or have older friends buy them

Impressively, it acts on the same receptors as benzodiazepines, yet doesnt cause the side effects of amnesia or sedation