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Johnny Depp After starring in the TV series, 21 Jump Street , Depp went on to lead films like Blow and Pirates of the Caribbean and claimed a couple awards plus Academy nominations

Combustion : The act of burning is what produces the toxic substances, including tar and carbon monoxide, which are responsible for the vast majority of smoking-related illnesses

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This is because cigarettes release thousands of different dodgy chemicals when they burn - which are poisonous and can cause cancer

Researchers discovered proteins in the airways of e-cigarette smokers that are known to contribute to COPD