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On top of purchase costs, smokers face potential fines for violating smoking restrictions in various public spaces

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For example, a recent study by Japanese scholars Tsukahara et al., who investigated plasma CLO concentrations before and after smoking cessation in 14 Japanese inpatients with schizophrenia who were being treated with CLO when a non-smoking policy was implemented in a psychiatric hospital, found that the mean plasma CLO concentrations and dose-corrected plasma CLO concentrations were significantly increased by 53.2 and 42.5%, respectively

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It must be noted that patients affected by COVID-19 are more likely to develop ARDS, resulting in pulmonary edema