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"I knew it was bad for me but I was in a vicious cycle of needing to get more and as soon as I had finished one I'd get another one - even when I'd get one confiscated, I'd immediately be set on getting another one." He says what began as "communal activity" became "very solitary" once he was addicted

Cannabinoids exert their effects primarily through activation of the ECS, which consists of the cannabinoid receptors CB 1 and CB 2 , endogenous ligands such as anandamide and 2-arachidonoylglycerol (2-AG), and enzymes responsible for ligand synthesis and degradation (50)

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