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Smoking: Effects, Risks, Diseases, Quitting & Solutions Unique, long term effects of nicotine on adolescent brain ScienceDirect Nicotine on the developing brain ScienceDirect Tobacco use imposes a hereditary burden upon offspring. It elevates the risk of birth defects by 68% and the incidence of brain abnormalities, such as anencephaly (a condition characterized by incomplete brain Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: A pharmacokinetic and pharmacodynamics perspective ScienceDirect
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