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Public awareness campaigns and regulatory measures have aimed to reduce these risks

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23 MRTP authorization, the FDA said 22 nd Century brands VLN King and VLN Menthola reference to very low nicotinecan reduce smokers exposure to nicotine by approximately 95% compared to conventional cigarettes

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Further investigations are warranted to understand the exact mechanisms responsible for smoking-mediated immunopathology and to answer lingering questions over why cigarette smoking is always harmful rather than beneficial even though it exerts dual effects on immune responses