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But this doesnt mean that e-cigarettes are entirely without harm

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West Virginia and Kentucky experience high levels of poverty and limited public health infrastructure

The Oregon Indoor Clean Air Act (found in section 433.835 of the Oregon Revised Statutes) was amended in January 2016 to add prohibitions on the use of e-cigarettes in restaurants, workplaces, and indoor public places

low certainty27 , 28), and magnitudes of weight gain for both nicotine and non-nicotine e-cigarettes.28 One RCT provided data on adverse events at 12 months that was of very low certainty,39 and a cohort study reported no serious adverse events or differences in smoking-related diseases at 4 years with nicotine e-cigarettes compared with traditional tobacco smoking (certainty could not be evaluated).49 Conclusions from the Cochrane living systematic review on potential harms were similar.24 Resource use Many behavioural interventions are covered by provincial and territorial health care systems or otherwise provided at no charge (e.g., quit lines), and every province and territory has at least limited coverage or rebate programs for pharmacotherapy, including NRT, which is considered a natural health product.50 53 However, people may have to pay out of pocket for some behavioural services or pharmacotherapy