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So far, only a small number of reasonable animal models of tobacco-related pancreatitis have been established (3, 20-27, 30-32, 48, 65, 118)

These substances can act synergistically to amplify damage to reproductive organs, hormones, and overall fertility

Around 6 million deaths are caused by tobacco use each year worldwide

Ingredients like propylene glycol, vegetable glycerine, and flavouring compounds can irritate the gut lining and disturb the natural balance of gut bacteria

Mendez and Warner were optimistic that smoking prevalence would continue to fall on course, as it had in the early 2000s, but they concluded that major reductions, such as those presented in the Healthy People 2010 target, were unrealistic (Mendez and Warner 2004)