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Real-world users vary widely, but one published study of exclusive e-cigarette users reported an average of about 365 puffs/day and weekly e-liquid consumption ranging from 5240 mL (median ~32.5 mL/week)which is a better anchor than guessing 200300 puffs. But rememberyou're not ingesting this liquid

Composed and unhurried, I slowly began to brush my hand over the small stretches of exposed skin, where I had rolled up the cuff of my long-sleeved button-down sun shirt in an attempt to cool myself from the radiating heat of the desert

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Ironically, given the smokers need for nicotine, a safer solution might be high nicotine cigarettes so that the smoker could satisfy his need with fewer cigarettes and so inhale less tar, the primary carcinogen.