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The Truth About Smoking Pleasure and Nicotine Addiction When nicotine from a cigarette reaches your brain, it releases dopamine, the chemical that makes you feel good for a short time. This is what starts the addiction. Nicotine also changes other Nicotine addiction can become a cycle of dopamine release, withdrawal, and cravings that reinforces continued nicotine use. The tobacco industry profits from keeping this cycle going. What feels like relief is often DOC2US Your trusted online doctor Tobacco: Nicotine and Dopamine
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