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Newly synthesized virus particles can not only travel through plasmodesmata, they can also enter the plant's phloem (passages that connect the entire plant), and therefore infect the entire plant (Scholthof, 2000)

Dehydration due to smoking parches the lips, and hence makes pigmentation more noticeable

Today, LGBT smokers are significantly more likely to smoke menthol cigarettes

Cigarette smoke contains thousands of chemicals, including dozens of known carcinogens, and smoking remains one of the leading preventable causes of death worldwide

That was around the time of the Master Settlement Agreement, which basically removed a lot of uncertainty from tobacco