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In our current study these metabolite alterations have been reanalyzed via a distinct bioinformatic approach (described below) to examine exposure and inhalation effects associated with ENDS usage

We included cancer survivors aged 19-64 throughout the entire study period, who had 1 pre-ACA visit to a study CHC and whose last recorded tobacco use status during this time period indicated current smoking (e.g., current every day, current some-day, heavy), and who had 1 post-ACA visit with a documented smoking assessment

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