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In Case C-663/18 , the European Court of Justice (ECJ) ruled that CBD is not a narcotic under the 1961 United Nations Single Convention on Narcotic Drugs, as it does not have psychoactive effects

This may be helpful to choose the range of exposure doses in in vitro assays, but also for the interpretation of the in vitro test results to the in vivo situation

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Other factors included body weight, age, baseline creatinine level, intimal thickening in the internal carotid artery and systolic blood pressure