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Although the underlying mechanisms by which arsenic causes such oxidative damage are not yet fully understood, possible mechanisms could include inhibition of antioxidant enzymes such as superoxide dismutase (SOD) and catalase, interface with cellular antioxidant defense systems by reducing levels of intracellular antioxidants such as glutathione, inhibition of DNA repair mechanisms, and alterations in epigenetic processes [7]

But like cocaine, chronic inhalation of meth powder can cause damage to your nasal passages over time and run the risk of addiction or overdose