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Co-exposure of female mice to a type of smokeless tobacco sadagura with arsenic which is a common additive of STs resulted in significant changes in diestrus phase, disrupted ovarian tissue morphology, increased oxidative stress and DNA damage in treated groups when compared to control (Barbhuiya et al ., 2020)

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In general, smoking cessation programs may be effective in the short term, but it is unclear whether these effects persist (Cropley, Theadom, Pravettoni, & Webb, 2008