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As far as periodic leg movements in sleep or restless legs syndrome, two studies have shown that these disorders deteriorate with smoking [26,101]

For example, path analysis (231, 232), systems dynamics (233), and structural equation modelling (SEM) (234, 235) model complex relationships between variables to identify direct and indirect pathways influencing mental health

It is therefore the main cause of chronic obstructive pulmonary disease (COPD), which includes emphysema and chronic bronchitis