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Based on these findings, the FDA concluded nicotine pouches may benefit adult smokers or smokeless tobacco users by reducing harm, though they remain unsafe and are not FDA approved

625) as a collection of individual agents with freedom to act in ways that are not always totally predictable, and whose actions are interconnected so that one agents actions changes the context for other agents. Components of these systems can be studied separately, but there are relationships among them, so the behavior of each component depends on the behavior of others