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According to our estimates, among those who continued to smoke during the pandemic, the number of cigarettes consumed per day increased by 52.2 percent in 2021 compared to 2019

16 Centers for Disease Control and Prevention

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Giving up smoking brings the inflammatory response back to where it would have been without cigarettes, but smoking-related epigenetic changes may be tougher to reverse, suspects Sheena Cruickshank, an immunologist at the University of Manchester