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The FDA, which is responsible for authorizing or approving tobacco products, authorized marketing of a few e-cigarette products in 2021 and has denied many others, but as noted by the agency, these actions "do not mean these products are safe or FDA approved." And, there is no information available about their long-term health impact

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They contain over 4,000 chemicals over 50 of which are known to be toxic in nature: the carbon monoxide also found in car exhaust fumes, butane found in lighter fluid, and arsenic, ammonia, and methanol found in rocket fuel, for example

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