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CONCLUSIONS The present study demonstrated that CSE may promote the apoptosis and senescence of EPCs by upregulating the expression of p300 and H4K12 protein, thus preventing the transition of EPCs from G1 phase to S phase, affecting telomerase synthesis, and reducing EPCs proliferation

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By age 3 I was actively anti-smoking, to the point I never once saw one parent light up, while years later I learned my friends saw it endlessly