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An extension of the model used in this study that includes spatial correlations, may be considered in the future

*Correspondence: Thomas Abbruscato, [email protected] This article was submitted to CNS Drug Delivery, a section of the journal Frontiers in Drug Delivery Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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A: Practice delay, distract, and deep breathing