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Our second evidence synthesis was a systematic review of primary studies on the benefits and harms of e-cigarettes for smoking cessation,23 which updated an existing Cochrane review from 2016.86 Although Cochrane has since transformed its review into a living systematic review,24 it had not yet done so when we developed our evidence review protocol.87 The Evidence Review and Synthesis Centre at the University of Ottawa conducted the systematic reviews according to our protocol.87 Peer-reviewed search strategies (using the Peer Review of Electronic Search Strategies checklist88) were conducted in MEDLINE, Embase, PsycINFO, and the Cochrane Library in September 2020

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The carton should not interfere with the primary packs opening, warning visibility, or tax-stamp access

| National Center for Health Research About electronic cigarettes (e-cigarettes) | Centers for Disease Control and Prevention How vaping helps even hardened smokers quit | EurekAlert Vaping is 95% safer than smoking

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