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Quantification of nicotine by mass spectrometry Nicotine was quantified from CSE by accurate mass measurement using LCMS with a synapt G2 Q-ToF mass spectrometer coupled to an Aquity chromatography system (Waters) using a method based on the work of McGuffrey et al

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However, for aged particles from tobacco smoke the 318 nm measured mobility CMD is larger than the 234 nm mobility CMD previously measured 30