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We use the ratio of ORs between years to assess whether the odds of smoking across sociodemographic subgroups changed over time, with CIs computed using the delta method.52 To investigate if e-cigarette vaping is replacing cigarette smoking as the predominant nicotine delivery system in those aged 1824 years, we analysed state estimates from the 201415 and 201819 TUS-CPS for the 24 most populous US states

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