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The close association between TTFC and increased biomarkers in PAHs and cadmium could be a crucial step in understanding smoking behavior and tobacco control, complementing the Food and Drug Administrations (FDA) current strategy of reducing nicotine content in cigarettes 5 and banning menthol 6

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According to the latest report from CDC, In 2019, an estimated 53.3% of high school students (8.0 million) and 24.3% of middle school students (2.9 million) reported having ever tried tobacco products