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However, if an individual is subjected to extreme, prolonged exposure in an unventilated space, low levels of cotinine may occasionally register

The nicotine in tobacco smoke is called a vasoconstrictor and it acts on blood vessels to contract them and reduce blood flow to the gum and bone

Hence, the high prevalence of constipation and IBS-C (52.2%) was unexpected, suggesting that symptoms of constipation may be more common in current smokers than in the general population

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