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Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations

SDS-PAGE resolves this by denaturing all proteins into rod-shaped SDS-protein complexes with uniform charge density (~1 SDS per 2 amino acids), so that mobility in the polyacrylamide gel is determined solely by the sieving effect of the pore matrix, giving a linear relationship between log molecular weight and relative migration distance (Rf)

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Orn, ornithine

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