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Smoking's Disease Burden: Worse than Previously Thought? NCI Tobacco use imposes a hereditary burden upon offspring. It elevates the risk of birth defects by 68% and the incidence of brain abnormalities, such as anencephaly (a condition characterized by incomplete brain Cigarette Smoking Smoking and Tobacco Use CDC Primary health effects from smoking. Figure 1 used with permission from Download Scientific Diagram 5 Sneaky Ways Smoking Is Expensive for Healthcare
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