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Importantly, use of the high concentration e-cigarette did not increase overall nicotine dependence, and was associated with a greater reduction in cigarette smoking compared to the cigarette substitute. While it has been hypothesized that the use of e-cigarettes could increase overall nicotine dependence, the research team said their study found that initiating e-cigarette use to reduce cigarette consumption resulted in reduced cigarette dependence and low e-cigarette dependence

That left an opening for artificial nicotine, which is being used in e-cigarette liquids, nicotine pouches and other products

Food and Drug Administration (FDA) comprehensive authority to regulate the manufacturing, marketing, and sale of tobacco products.

Jain said, Scaling without compromising product integrity is critical

Funding Priorities: The recent significant decline in smoking prevalence in the U.S