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Hoffman, R

Low CSF concentration of a dopamine metabolite in tobacco smokers

The NASEM report concludes there is substantial evidence that e-cigarette use among adolescents increases the risk of smoking later on

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They were asked to either continue smoking their regular brand of cigarette or to smoke one of six types of investigational cigarettes that had varying amounts of nicotine, ranging from 15.8 milligrams (mg) of nicotine per gram of tobacco (the amount found in most commercial brands) all the way down to 0.4 mg per gram