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Tobacco use remains the number one preventable cause of death for African Americans, claiming more than 45,000 lives annually

In this literature review, we aim to summarize the epidemiology of cigarette smoking and tobacco use in the United States, pharmacology of nicotinethe active constituent of tobacco, and health consequence of cigarette smoking

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WHO packaging guidance and country laws make clear that warning size and presentation can differ by jurisdiction, so readers should avoid assuming that one warning layout is universal everywhere