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In the figure below, only the solid lines are statistically significant (dot-dash lines are not significant) and thicker solid lines mean larger effect sizes: Not only was there no evidence for my expected mechanism of nicotine dependence (as e-cigarette use was not significantly associated with later nicotine dependence), but there was no evidence for gateway at all (as e-cigarette use didnt significantly predict smoking, either directly or indirectly)

The study was approved by the University of Washington Institutional Review Board (study no

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Howard said he regards the program as a great liabilitythat from AMAs view it has only caused further blackening of AMAs image