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With integrated expression values in hand, we carried out principle component analysis (PCA) and then clustered and visualized the integrated data using the top 30 dimensions

Interestingly, habitual smokers experienced an increase in eGFR with reduced sleep, whereas occasional smokers showed improved kidney function with longer sleep

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20,21 A cross-sectional study conducted in a Japanese population undergoing medical examinations revealed that individuals with elevated glycated hemoglobin (HbA1c 5.6%) exhibited significantly lower FEV 1 /FVC ratios, further underscoring the link between impaired glucose homeostasis and pulmonary dysfunction