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A 2015 report by the Institute of Medicine (IOM) committee estimated that if a nationwide Tobacco 21 rule was implemented, it would result in 249,000 fewer premature deaths, 45,000 fewer deaths from lung cancer and 4.2 million fewer lost life-years among Americans born between 2010 and 2019

Competition between factories to produce high quality and tasty cigarette toughens Meanwhile, some of private manufacturers who went under in the competition have disappeared from the cigarette market or been merged with big factories

Compared to tobacco [31], the water content of the samples was significantly lower so in the end, its effect on the mercury content was not so analytically important

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