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Stellungnahme des Bundesrates vom 21.05.2014

Once we had estimated the age attenuation factors, we carried out the last step, which consisted of adjusting the risk curve for the reference age group from step 1 using equation (1) to produce the age group-specific risk curves for each CVD outcome: We implemented the age adjustment at the draw level so that the uncertainty of the age attenuation factors could be naturally incorporated into the final adjusted age-specific RR curves

Esophageal Damage: Prolonged use of tobacco leads to chronic inflammation that eventually weakens lining tissues, thereby exposing them quickly to irritation, especially if they come into contact with harmful chemicals found in smoke like carbon monoxide butane, formaldehyde, etcetera, hence increasing chances for developing GERD among other related diseases

Farsalinos KE, Romagna G, Allifranchini E, Ripamonti E, Bocchietto E, Todeschi S, et al

Burns 41 , 14051419 (2015)