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Most people should first consider options other than e-cigarettes to stop smoking

Cigarette smoke-induced oxidative stress suppresses generation of dendritic cell IL-12 and IL-23 through ERK-dependent pathways

This guideline was developed following the GRADE approach.21 We adhered to Appraisal of Guidelines for Research and Evaluation (AGREE II), Guidelines International Network (GIN), and Guidance for Reporting Involvement of Patients and the Public (GRIPP-2) reporting guidance.83 85 More information about the task forces methods is available on the task force website ( Evidence review and development of recommendations The recommendation was informed by 2 evidence syntheses that addressed the benefits and harms of smoking cessation interventions