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Hughes JR, Gulliver SB, Fenwick JW, et al

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Since the FDA regulations were signed, if a vape shop mixes or prepares e-liquids or creates or modifies aerosolizing apparatus for direct sale to consumers for use in ENDS, the establishment fits within the definition of tobacco product manufacturer. These tobacco product manufacturers are subject to more stringent regulations than vape shops that only sell pre-fabricated e-liquid solutions

Young people often use multiple nicotine-containing products, which increases initiation rates and impedes tobacco cessation

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