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ODwyer DN, Kim JS, Ma SF, Ranjan P, Das P, Lipinski JH, et al

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The idea here is that Americans have heard so often, and for so long, about how harmful cigarettes are that the message is less impactful. It may also be possible that fewer Americans know smokers or people with tobacco-related disease, and this also could decrease perceived harm

20,49,85 Guidance for discussions regarding ENDS in the clinical setting is shown in Table I