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Outcome evaluation According to the 9th and 10th International Classification of Diseases (ICD) issued by the World Health Organization (WHO), we extracted the disease codes of all samples from the UKB database

In addition, Cytokines like IL-2, IL-12, IL-23, and TNF- can be produced by tumor-associated macrophages, dendritic cells, or CD4+ T cells, all of which are paired with CTL, NK cells, Th17 cells proliferation 34