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House-dust mite (HDM) treatment During the last 21 days of the 60-day exposure study, subsets of WT or MMP-12 KO mice were treated intranasally once a week for 3 consecutive weeks with 50 g of HDM extract resuspended in 1X PBS to induce allergic responses or 1X PBS for the control groups, as described in [37]

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Ask about your family medical history Perform a physical exam Your health care professional will also ask questions to rule out critical or life-threatening causes for your pain