cigarette smoke mitochondrial dysfunction small airway epithelial cells Smoking shifts human epithelium club toward a lesser differentiated population Cigarette smoke causes a bioenergetic

Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF 1 under normoxia Cell Death Discovery Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage PNAS Frontiers Small airway disease as a key factor in COPD: new perspectives and insights Dysregulation of mitochondrial complexes and dynamics by chronic cigarette smoke exposure Utilizing MitoQC reporter mice ScienceDirect Targeting mitochondrial permeability transition pore ameliorates PM2.5 induced mitochondrial dysfunction in airway epithelial cells ScienceDirect

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