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Conversely, nicotine may exert paradoxical inhibitory effects by activating immune pathways and inducing apoptosis, such as through stimulation of immature dendritic cells via PI3K/Akt signaling and modulation of caspase-3 and Cyclin B1 expression through 7-nAChR signaling [36]

Effect of free-base and protonated nicotine on nicotine yield from electronic cigarettes with varying power and liquid vehicle

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However, it's important to consider the potential risks and benefits of using vaping for weight loss