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Epithelialmesenchymal transformation (EMT) is a unique biological process in which epithelial cells lose their polarity and transform into mobile mesenchymal cells [7]

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In 1981, after killing two men, he had put a pistol to his temple and shot himself through the forehead: it had left him with what amounted, after surgery, to a frontal lobotomy and, according to subsequent testimony, with about the understanding of a young childa dim simplicity that the surgeon who operated on him likened to that of the Jack Nicholson character after his lobotomy in One Flew Over the Cuckoos Nest. At the least, it appeared incontestable that after lifting the pistol to his forehead and blasting away some three inches of the front of his brain he was not the same being who only a few moments earlier had casually murdered a policeman sitting in his mothers parlor