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In sepsis-associated AKI, BMSCs inhibited apoptosis and pyroptosis in renal tubular epithelial cells to ameliorate kidney injury by inducing Parkin-dependent mitophagy [132]

Because the scarring is irreversible, the increased risk for long-term disability often centers on work limitations, reduced quality of life, and the need for ongoing monitoring by a pulmonary specialist

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This increased cancer risk is a major concern, given the immunosuppressive regimens required post-LT, which can further predispose patients to oncogenesis [112]