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The agency found that the issuance of the modified risk tobacco product orders with reduced exposure information would be appropriate to promote the public health and is expected to benefit the health of the population as a whole . The FDA also concluded that the totality of evidence presented suggests that a measurable and substantial reduction in morbidity or mortality among individual tobacco users is reasonably likely to be established in subsequent studies

However, due to the different nature of the IQOS Heets smoke (glycerol aerosol) compared to conventional cigarette smoke, oxidative reagents were also used (KMnO 4 , Fentons reagent, Joness reagent) to aid the retrieval of 210 Po from the washing flasks

But the products met with resistance from health groups, who claimed the new cigarettes were still unsafe, and the products floundered and were withdrawn after just a few months

Ratajczak A, Jankowski P, Strus P, Feleszko W