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Nicotine also binds 42, a high-affinity receptor along GABA neurons, which, with chronic nicotine use, become desensitized, therefore dampening the inhibition on dopaminergic transmission from the VTA to the NAc, while 7, low-affinity nAChRs on glutamatergic neurons are less prone to desensitization, therefore continue to enhance dopamine transmission (94, 95)

Smoking impairs the throats ability to fend off pathogens, resulting in frequent infections that keep the throat irritated

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In the early months after the diagnosis, Hampton admitted the roller coaster was disorienting

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